Publications

The strong protective role of Christensenellaceae against visceral fat

Variation in the human fecal microbiota has previously been associated with body mass index (BMI). Although obesity is a global health burden, the accumulation of abdominal visceral fat is the specific cardio-metabolic disease risk factor. Here, the authors explore links between the fecal microbiota and abdominal adiposity using body composition as...

+ Find out more

C.minuta is the species related to weight gain

Host genetics and the gut microbiome can both influence metabolic phenotypes. Here, Goodrich et al. compared microbiotas across >1,000 fecal samples obtained from the TwinsUK population, including 416 twin pairs. They identified many microbial taxa whose abundances were influenced by host genetics. The most heritable taxon, the family...

+ Find out more

What is the link between Christensenellaceae, gut microbiome, low BMI and a low triglyceridemia?

Evidence suggests the gut microbiome is involved in the development of cardiovascular disease (CVD), with the host-microbe interaction regulating immune and metabolic pathways. After correcting for age and gender, cross-validation analysis revealed that microbiota explain 4.5% of the variance in BMI, 6% in triglycerides, and 4% in high-density...

+ Find out more